ANZINGER LAB
Department of Microbiology
University of the West Indies, Mona Campus
PUBLICATIONS
1. Li A, Lindo JF, Beckles H, Mahler JL, Reid M, Boyne M, DeHovitz J, Diaz PI, Brown P, Anzinger J, Carrington C, Anderson KB, Landay A, Cummings M, Chernyak E, Prescott G, Cha R, Thangamani S, Barthelemy E, Dubovsky S, Ennis A, Evans-Gilbert T, Morse GD. University consortium to address public health priorities and research capacity building in the Caribbean. Front. Educ. 2023 Nov 30.

2. Leys Y, Cameron J, Frater V, Thomas K, Butterfield TR, Campbell Mitchell M, Maddan C, Moore J, Pierre R, Cloherty GA, Anzinger JJ. Seroprevalence of HTLV-1 in a Jamaican Antenatal Population and Assessment of Pooled Testing as a Cost Reduction Strategy for Implementation of Routine Antenatal Screening. Am. J. Trop. Med. Hyg. 2023 Oct 23. PUBMED

3. Ali I, Alarcón-Elbal PM, Mundle M, Noble SAA, Oura CAL, Anzinger JJ, Sandiford SL. The Others: A systematic Review of the Lesser-Known Arboviruses of the Insular Caribbean. Viruses. 2023 Mar 25. PUBMED

4. Osterholm MT, Rabadán-Diehl C, Anzinger J, Botazzi ME, Christie-Samuels C, Erondu N, Marrazzo J, Milan S, Quashie PK, Schwaab T, Williams D. Insights from Cuba's COVID-19 Vaccine Enterprise: Report from a High Level Fact-Finding Delegation to Cuba. MEDICC Rev. 2022 Oct 31. PUBMED

5. Anzinger JJ, Cameron-McDermott SM, Phillips YZR, Mendoza L, Anderson M, Cloherty G, Strachan-Johnson S, Lindo JF, Figueroa JP. Prevalence of SARS-CoV-2 antibodies after the Omicron surge, Kingston, Jamaica, 2022. J. Clin. Virol. Plus. 2022 Nov. PUBMED

6. Berry C-LS, Melbourne-Chambers RH, Harrison AN, Anzinger JJ, Gordon-Johnson K-AM, Deyde VM, Christie CDC. Hospitalized children with SARS-CoV-2 infection and MIS-C in Jamaica: A dive into the first 15 months of the novel pandemic. Front. Pediatr. 2022 Sep 7. PUBMED

7. Anzinger JJ. Seroprevalence of Chikungunya Virus, Jamaica, and New Tools for Surveillance (Response). Emerg. Infect. Dis. 2022 Aug. PUBMED

8. Lue AM, Richards-Dawson MEH, Gordon-Strachan GM, Kodilinye SM, Dunkley-Thompson JAT, James-Powell TD, Pryce CA, Mears CD, Anzinger JJ, Webster-Kerr K, Christie CDC. Severity and Outcomes of Dengue in Hospitalized Jamaican Children in 2018–2019 During an Epidemic Surge in the Americas. Front. Med. 2022 Jun 21. PUBMED

9. Butterfield TR, Hanna DB, Kaplan RC, Xue X, Keizer JR, Durkin HG, Kassaye SG, Nowicki M, Tien PC, Golub ET, Floris-Moore MA, Titanji K, Fischl MA, Heath S, Palmer CS, Landay AL, Anzinger JJ. Elevated CD4+ T cell glucose metabolism in HIV+ women with diabetes mellitus. AIDS. 2022 Jun 21. PUBMED

10. Leys YE, Nwokocha M, Walker JP, Butterfield TR, Frater VD, Thompson TK, Anderson M, Gloherty GA, Anzinger JJ. SARS-CoV-2 receptor-binding domain IgG response to AstraZeneca AZD1222 COVID-19 vaccination, Jamaica. Am. J. Trop. Med. Hyg. 2022 Mar 23. PUBMED

11. Averhoff F, Berg M, Rogers M, Osmanov S, Luo X, Anderson M, Meyer T, Landay A, Gamkrelidze A, Kallas EG, Ciuoderis K, Hernandez JP, Henry JH, Osiris J, Lindo J, Deshommes J, Anzinger J, Manasa J, Alkashvili M, Souleyman M, Kaleebu P, Correa-Oliveira R, Solomon S, de Olivera T, Suputtamongkol Y, Cloherty G. The Abbott Pandemic Defense Coalition: a unique multisector approach adds to global pandemic preparedness efforts. Int. J. Infect. Dis. 2022 Feb 5. PUBMED

12. Anzinger JJ, Mears CD, Ades AE, Francis K, Phillips Y, Leys YE, Spyer MJ, Brown D, Bispo de Filippis AM, Nastouli E, Byrne T, Bailey H, Palmer P, Bryan L, Webster-Kerr K, Giaquinto C, Thorne C, Christie CDC, ZIKAction Consortium. Antenatal seroprevalence of Zika and chikungunya viruses, Kingston Metropolitan Area, Jamaica, 2017-2019. Emerg. Infect. Dis. 2022 Feb. PUBMED

13. Cameron-McDermott SM, Barrow GJ, Webster AM, De La Haye CO, Wood DHE, Lewis VM, Nicholson A, Reynolds-Campbell GY, Thoms-Rodriguez CA, Roye-Green KJ, Otto-Stewart N, Miller ZN, Tomlinson JA, Skyers N, Unemo M, Anzinger JJ. Antimicrobial susceptibility of Neisseria gonorrhoeae isolates and syndromic treatment of men with urethral discharge in Kingston, Jamaica, 2018-19. J. Anitmicrob. Chemother. 2021 Dec 2r. PUBMED

14. Butterfield TR, Bruce-Mowatt A, Phillips YZR, Brown N, Francis K, Brown J, Walker JP, McKnight NAL, Ehikhametalor K, Taylor DK, Bruce CA, McGrowder D, Wharfe G, Sandiford SL, Thompson TK, Anzinger JJ. Assessment of commercial SARS-CoV-2 antibody assays, Jamaica. J. Int. J. Infect. Dis. 2021 Feb 18. PUBMED

15. Ades AE, Brickley EB, Alexander N, Brown D, Jaenisch T, de Barros Miranda-Filho D, Pohl M, Rosenberger KD, Soriano-Arandes A, Thorne C, de Alencar Ximenes RA, Barreto de Araújo TV, Avelino-Silva VI, Bethencourt Castillo SE, Borja Aburto VH, Brasil P, Christie CDC, Vieira de Souza W, Gotuzzo H JE, Hoen B, Koopmans M, Turchi Martelli CM, Teixeira MM, Marques ETA, Miranda MC, Montarroyos UR, Moreira ME, Morris JG, Rockx B, Saba Villarroel PM, Segarra CS, Tami A, Turchi MD, Giaquinto C, de Lamballerie X, Wilder-Smith A, EC Zika Consortia Vertical Transmission Study Group. Zika virus infection in pregnancy: a protocol for the joint analysis of the prospective cohort studies of the ZIKAlliance, ZikaPLAN and ZIKAction consortia. BMJ Open. 2020 Dec 15. PUBMED

16. Butterfield TR, Landay AL, Anzinger JJ. Dysfunctional immunometabolism in HIV infection: Contributing factors and implications for age-related comorbid diseases. Curr. HIV/AIDS Rep. 2020 Apr. PUBMED

17. Ali I, Mundle M, Anzinger JJ, Sandiford SL. Tiger in the sun: A report of Aedes albopictus in Jamaica. Acta. Trop. 2019 Jul 25. PUBMED

18. Rajasuriar R, Hearps AC, Crowe SM, Anzinger JJ, Palmer CS. Suppression of monocyte inflammatory and coagulopathy responses in HIV infection. Ann. Transl. Med. 2018 Jul. PUBMED

19. Anzinger JJ, Butterfield TR, Gouillou M, McCune JM, Crowe SM, Palmer CS. Glut1 expression level on inflammatory monocytes is associated with markers of cardiovascular disease risk in HIV-infected individuals. J. Acquir. Immune Deficiency. Syndr. 2018 Feb. PUBMED

20. James-Powell T, Brown Y, Christie CDC, Melbourne-Chambers R, Moore JT, Morgan O, Butler B, Swaby K, Garbutt A, Anzinger J, Peirre J, Onyonyor A, Bryan L, Palmer PM, Mitchell P, Johnson P, Bishop K, Jaggon JR, De La Haye W. Trends of Microcephaly and Severe Arthrogryposis in Three Urban Hospitals following the Zika, Chikungunya and Dengue Fever Epidemics of 2016 in Jamaica. WIMJ. (in press)

21. Anzinger JJ, Jin X, Palmer CS, Dagur P, Barthwal MK, Krush HS. Measurement of aortic cell fluid-phase pinocytosis in vivo by flow cytometry. J. Vasc. Res. Jun 16;54(4):195-199. PUBMED

22. Metsky MC, Matranga B, Wohl S, Schaffner SF, Freije A, Winnicki SM, West K, Qu J, Baniecki ML, Gladden-Young A, Lin AE, Tomkins-Tinch CH, Park DJ, Luo CY, Barnes KG, Chak B, Barbosa-Lima G, Delatorre E, Veira YR, Paul LM, Tan AL, Porcelli MC, Vasquez C, Cannons AC, Marshall RC, Hogan KN, Kopp EW, Anzinger JJ, Garcia KF, Parham LA, Gélvez Ramirez RM, Miranda Montoya MC, Rojas DP, Brown CM, Hennigan S, Sabina B, Scotland S, Gangavarapu K, Grubaugh ND, Oliveira G, Robles-Sikisaka R, Rambaut A, Gehrke L, Smole S, Halloran ME, Villar Centeno LA, Mattar S, Lorenzana I, Cerbino-Neto J, Degrave W, Bozza PT, Gnirke A, Anderson KG, Isern S, Michael S, Bozza F, Souza TM, Bosch I, Yozwiak NL, MacInnis BL, Sabeti PC. Genome sequencing reveals Zika virus diversity and spread in the Americas. Nature. Jun 15;546(7658):411-415. PUBMED

23. Butterfield TR, Hanna DB, Kaplan RC, Kizer JR, Durkin HG, Young MA, Nowicki MJ, Tien PC, Golub ET, Floris-Moore MA, Titanji K, Fischl MA, Heath SL, Martinson J, Crowe SM, Palmer CS, Landay AL, Anzinger JJ. Increased expression of glucose transporter-1 on intermediate monocytes from HIV infected women with subclinical cardiovascular disease. AIDS. 2017 Jan 14;31(2):199-205. PUBMED

24. Uhrlaub JL, Pulko V, DeFilippis VR, Coleman GD, Lindo J, Vickers I, Anzinger J, Nikolich-Zugich J. Dysregulated TGF-beta production underlies the age-related vulnerability to Chikungunya virus (in press). PLoS Pathog. 2016: e1005891. PDF

25. Palmer CS, Anzinger JJ, Butterfield TR, Crowe SM. A simple flow cytometric method to measure glucose uptake and glucose transporter expression for monocytes and monocyte subpopulations in whole blood. J. Vis. Exp. 2015:e54255. PUBMED

26. Palmer CS, Henstridge DC, Yu D, Singh A, Balderson B, Duette G, Cherry CL, Anzinger JJ, Ostrowski M, Crowe SM. Emerging Role and Characterization of Immunometabolism: Relevance to HIV Pathogenesis, Serious Non-AIDS Events, and a Cure.. J Immunol. 2016 Jun 1;196(11):4437-44. doi: 10.4049/jimmunol.1600120. PDF

27. Aiken WD, Anzinger JJ. Chikungunya virus infection and acute elevation of serum Prostate-Specific Antigen. Case Rep. Urol. 2015;2015:120535. PDF

28. Palmer CS*, Anzinger JJ*, Zhou J, GouillouM, Landay AL, Jaworowski A,McCune JM, Crowe SM. Glut1 expressing pro-inflammatory monocytes are elevated in cART-treated and untreated HIV-1+ subjects. J. Immunol. 2014;193:5595-5603. *equal contribution. PDF

29. Anzinger JJ, Palmer CS, Butterfield TR, Crowe SM. Monocytes as regulators of inflammation and HIV-related co-morbidities during cART. J. Immunol Res. 2014;2014:569819. PDF

30. Freeman S, Jin X, Anzinger JJ, Xu Q, Purushothaman S, Fessler MB, Addadi L, Kruth HS. ABCG1-mediated generation of extracellular cholesterol-rich microdomains. J. Lipid Res. 2014;55:115-127. PDF

31. Barthwal MK*, Anzinger JJ*, Chang J, Xu Q, Bohnacker T, Wymann MP, Kruth HS. Fluid-Phase Pinocytosis of Native Low Density Lipoprotein Promotes Murine M-CSF Differentiated Macrophage Foam Cell Formation. PLoS One. 2013;8:e58054. *equal contribution. PDF

32. Anzinger JJ, Chang J, Xu Q, Bohnacker T, Wymann MP, Kruth HS. Murine bone marrow-derived macrophages differentiated with GM-CSF become foam cells by PI3Kgamma-dependent fluid-phase pinocytosis of native LDL. J. Lipid Res. 2012;53:34-42. PDF

33. Leyva FJ, Anzinger JJ, McCoy PJ, Kruth HS. Evaluation of transduction efficiency in macrophage colony-stimulating factor differentiated human macrophages using HIV-1 based lentiviral vectors. BMC Biotechnol. 2011;31:11. PDF

34. Anzinger JJ, Chang J, Xu Q, Buono C, Li Y, Leyva FJ, Park B, Greene LE, Kruth HS. Native low-density lipoprotein uptake by M-CSF-differentiated human macrophages is mediated by macropinocytosis and micropinocytosis. Arterioscler Thromb Vasc Biol. 2010;30:2022-31. PDF

35. Ong DS, Anzinger JJ, Leyva FJ, Kruth HS. Extracellular cholesterol-rich microdomains generated by human macrophages and their potential role in reverse cholesterol transport. J. Lipid Res. 2010;51:2303-13. PDF

36. Buono C, Anzinger JJ, Amar M, Kruth HS. Fluorescent pegylated nanoparticles demonstrate fluid-phase pinocytosis by macrophages in mouse atherosclerotic lesions. J. Clin. Invest. 2009;119:1373-81. PDF

37. Anzinger JJ, Olinger GG, Saifuddin M, Spear GT. Donor variability in HIV binding to peripheral blood mononuclear cells; high and low HIV-binding phenotypes are stable over time. Virol. J. 2008; 5:95. PDF

38. Spear GT, Zariffard MR, Chen HY, Anzinger JJ, Anastos K, Rusine J, Gatabazi J, French AL, Cohen M, Landay AL. Positive association between HIV RNA and IL-6 in the genital tract of Rwandan Women. AIDS Res. Hum. Retroviruses. 2008;24:973-6. PDF

39. Buxton IL, Anzinger JJ. Agonist-specific regulation of inositol phosphate metabolism in cardiac endothelial cells. Proc. West. Pharmacol. Soc. 2008;51:23-26. PDF

40. Anzinger JJ, Mezo I, Ji X, Gabali AM, Thomas LL, Spear GT. HIV infection of mononuclear cells is calcium-dependent. Virus Res. 2006;122:183-8. PDF

41. Gabali AM, Anzinger JJ, Spear GT, Thomas LL. Activation by inflammatory stimuli increases neutrophil binding of human immunodeficiency virus type 1 and subsequent infection of lymphocytes. J. Virol. 2004;78:10833-6. PDF

42. Anzinger J, Malmquist NA, Gould J, Buxton IL. Secretion of a nucleosidediphosphate kinase (Nm23-H2) by cells from human breast, colon, pancreas and lung tumors. Proc. West. Pharmacol. Soc. 2001;44:61-3. PDF

43. Malmquist NA, Anzinger JJ, Hirzel D, Buxton IL. Ellagic acid inhibits nucleoside diphosphate kinase-B activity. Proc. West. Pharmacol. Soc. 2001;44:57-9. PDF